Investigators: Professor Serena Best, Dr Patrick Marti
Stream: PhD
Topic: Biomaterials (HA)
Status: Completed
The coating of metal orthopaedic implants with hydroxyapatite has been shown to improve the mechanical and chemical attachment of new bone, resulting in improved implant fixation and bone repair. Despite the relative success of hydroxyapatite-coated biomaterials, continued development is necessary in order to meet the needs of an aging and more active population.Zinc plays an important role in bone cell biology and has been shown to stimulate bone growth. This project investigated the production and characterisation of novel zinc-containing hydroxyapatite coatings, finding that zinc incorporation improves the biological response to hydroxyapatite coatings.
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